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Background Transcriptional activator-like (TAL) effectors, formerly known as the AvrBs3/PthA protein family, are DNA-binding effectors broadly found in Xanthomonas spp. That transactivate host genes upon injection via the bacterial type three-secretion system. Biologically relevant targets of TAL effectors, i.e. Host genes whose induction is vital to establish a compatible interaction, have. 14-3-3 protein zeta (14-3-3-like protein) (Protein Leonardo) 14-3-3zeta 14-3-3, 14-3-3EZ, leo, THAP, CG17870. Annotation score: Annotation score:5 out of 5. The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. Background Recent evidence indicates that metformin inhibits mammalian cancer growth and metastasis through the regulation of microRNAs. Metformin regulates miR-381 stability, which plays a vital role in tumor progression. Moreover, increased YAP expression and activity induce non-small cell lung cancer (NSCLC) tumor growth and metastasis. However, the molecular mechanism underpinning how. « hide 10 20 30 40 50 mastkdrenf vyiaklaeqa eryeemvdsm knvanldvel tieernllsv 60 70 80 90 100 gyknvigarr aswrilssie qkeeskgndv nakrikeyrh kvetelsnic 110 120 130 140 150 idvmrvideh lipsaaages tvfyykmkgd yyrylaefkt gnekkeagdq 160 170 180 190 200 smkayesatt aaeaelppth pirlglalnf svfyyeilns perachlakq 210 220 230 240 250 afdeaiseld tlneesykds tlimqllrdn ltlwtsdipe dgedsqkang 260 takfgggdda e.
Citation: Mehta P, Wavreille A-S, Justiniano SE, Marsh RL, Yu J, Burry RW, et al. (2011) LyGDI, a Novel SHIP-Interacting Protein, Is a Negative Regulator of FcγR-Mediated Phagocytosis. PLoS ONE 6(6): e21175. https://doi.org/10.1371/journal.pone.0021175
Editor: Neil A. Hotchin, University of Birmingham, United Kingdom
Received: October 19, 2010; Accepted: May 23, 2011; Published: June 14, 2011
Copyright: © 2011 Mehta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Funding: This work was supported by NIH grants P01 CA095426 and R01 AI059406; AHA predoctoral fellowship 09PRE2170054 (PM); Postdoctoral fellowship from the American Cancer Society, Ohio Division (JPB) and NIH postdoctoral fellowship T32 60013191 (SEJ). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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Competing interests: The authors have declared that no competing interests exist.